Dr. Niall Colgan

B.Sc.,M.Sc., Ph.D

 
researcher
 

Biography

Dr. Niall Colgan is a lecturer in medical physics and a clinical medical physicist.  His work has been applied in diagnostic imaging projects related to dementia, acquired brain injury, psychosis, neurological disorder, oncology, musculoskeletal and cardiac disease.  His primary research focus is biophysics and diagnostic imaging, particularly MR metabolite imaging and diffusion MRI however he also has active research programs in ionizing imaging, computational modeling/simulation, Microscopy, data mining, clinical instrumentation and tissue mechanics. He has led research teams  in the area of preclinical imaging bio-markers  and preclinical drug trials and has directed and established clinical imaging research  facilities utilized in clinical research and trials. A particular interest is the development of imaging methods that will open up new possibilities for the diagnosis and evaluation of therapeutic efficacy. 

https://scholar.google.co.uk/citations?user=RPuNH60AAAAJ&hl=en


Research Interests

Research Interests

  • Medical physics
  • Diagnostic imaging (ionising and non-ionising)
  • Medical image processing
  • Imaging biomarkers
  • Tissue mechanics
  • Simulation
  • Data Mining

Peer Reviewed Journals

  Year Publication
(2017) 'In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis'
Colgan, N,Ganeshan, B,Harrison, IF,Ismail, O,Holmes, HE,Wells, JA,Powell, NM,O'Callaghan, JM,O'Neill, MJ,Murray, TK,Ahmed, Z,Collins, EC,Johnson, RA,Groves, A,Lythgoe, MF (2017) 'In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis'. Frontiers In Neuroscience, 11 [DOI] [Details]
(2017) 'In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis'
Niall Colgan, Balaji Ganeshan, Ian F. Harrison, Holly E. Holmes, Ozama Ismail, Nick M. Powell, James O'Callaghan, Tracey K. Murray, Zeshan Ahmed, Ross A. Johnson, Emily C. Collins, Michael J. O’Neill, Ashley Groves, Mark F. Lythgoe (2017) 'In Vivo Imaging of Tau Pathology Using Magnetic Resonance Imaging Textural Analysis'. Frontiers In Neuroscience, 11 [Details]
(2016) 'Development and implementation of a DQE technique to assess image quality for digital radiology systems in the Saolta University Healthcare Group'
Donoghue, Matthew,Tuohy, Brendan,Colgan, Niall,Lavin, David,van der Putten, Wil (2016) 'Development and implementation of a DQE technique to assess image quality for digital radiology systems in the Saolta University Healthcare Group'. Physica Medica, European Journal Of Medical Physics, 32 (77) [Details]
(2016) 'Investigation of GlucoCEST as novel clinical MR biomarker of glucose metabolism'
Colgan, Niall Donoghue, Matthew Zuchora, Zdzislaw Tuohy, Brendan van der Putten, Wil (2016) 'Investigation of GlucoCEST as novel clinical MR biomarker of glucose metabolism'. Physica Medica, European Journal Of Medical Physics, [Details]
(2016) 'Role of nuclear medicine methods in prostate cancer management'
Zuchora, Zdzislaw,Browne, Mark,Colgan, Niall (2016) 'Role of nuclear medicine methods in prostate cancer management'. Physica Medica, European Journal Of Medical Physics, 32 (77):956-957 [Details]
(2016) 'Testing and evaluation of image registration brachytherapy'
Sands, Gordon,Zuchora, Anysja,Brien, Aoife O.,Colgan, Niall,Moore, Margaret,Tuohy, Brendan (2016) 'Testing and evaluation of image registration brachytherapy'. Physica Medica, European Journal Of Medical Physics, 32 (77):951-952 [Details]
(2016) 'Horizontal nystagmus and multiple sclerosis using 3-Tesla magnetic resonance imaging'
Iyer, PM,Fagan, AJ,Meaney, JF,Colgan, NC,Meredith, SD,Driscoll, DO,Curran, KM,Bradley, D,Redmond, J (2016) 'Horizontal nystagmus and multiple sclerosis using 3-Tesla magnetic resonance imaging'. Irish Journal Of Medical Science, :1-6 [Details]
(2016) 'Imaging the accumulation and suppression of tau pathology using multiparametric MRI'
Holmes, Holly E,Colgan, Niall,Ismail, Ozama,Ma, Da,Powell, Nick M,O'Callaghan, James M,Harrison, Ian F,Johnson, Ross A,Murray, Tracey K,Ahmed, Zeshan (2016) 'Imaging the accumulation and suppression of tau pathology using multiparametric MRI'. Neurobiology Of Aging, 39 :184-194 [Details]
(2015) 'Increased cerebral vascular reactivity in the tau expressing rTg4510 mouse: evidence against the role of tau pathology to impair vascular health in Alzheimer's disease'
Wells, Jack A,Holmes, Holly E,O'Callaghan, James M,Colgan, Niall,Ismail, Ozama,Fisher, Elizabeth MC,Siow, Bernard,Murray, Tracey K,Schwarz, Adam J,O'Neill, Michael J (2015) 'Increased cerebral vascular reactivity in the tau expressing rTg4510 mouse: evidence against the role of tau pathology to impair vascular health in Alzheimer's disease'. Journal of Cerebral Blood Flow & MetabolismJournal of Cerebral Blood Flow & Metabolism, 35 (33):359-362 [Details]
(2015) 'Glymphatic clearance impaired in a mouse model of tauopathy: Captured using contrast-enhanced MRI'
Harrison, Ian F,Machhada, Asif,Colgan, Niall,Ismail, Ozama,O'Callaghan, James M,Holmes, Holly,Wells, Jack A,Gourine, Alexander V,Murray, Tracey K,Ahmed, Zeshan (2015) 'Glymphatic clearance impaired in a mouse model of tauopathy: Captured using contrast-enhanced MRI'. Alzheimer's & Dementia, 11 (77) [Details]
(2015) 'In vivo imaging of tau pathology using multi-parametric quantitative MRI'
Ismail, O,Walker-Samuel, S,Golay, X,Rega, M,Richardson, S,Modat, M,Cardoso, MJ,Ourselin, S,Schwarz, AJ,Ahmed, Zeshan (2015) 'In vivo imaging of tau pathology using multi-parametric quantitative MRI'. Alzheimer's & Dementia, [Details]
(2015) 'Imaging the efficacy of microtubule stabilizing agent epothilone d in the rtg4510 mouse model of tauopathy'
Ismail, Ozama,Harrison, Ian F,Holmes, Holly,Colgan, Niall,Wells, Jack A,O'Callaghan, James M,Powell, Nicholas M,Ma, Da,Ourselin, Sebastien,Walker-Samuel, Simon (2015) 'Imaging the efficacy of microtubule stabilizing agent epothilone d in the rtg4510 mouse model of tauopathy'. Alzheimer's & Dementia, 11 (77) [Details]
(2015) 'A multi-scale MRI approach to investigate novel drug treatment strategies in mouse models of Alzheimer's disease'
Ismail, Ozama,Holmes, Holly,Colgan, Niall,Ma, Da,Wells, Jack A,Powell, Nicholas M,O'Callaghan, James M,Harrison, Ian F,Walker-Samuel, Simon,Cardoso, Jorge M (2015) 'A multi-scale MRI approach to investigate novel drug treatment strategies in mouse models of Alzheimer's disease'. Alzheimer's & Dementia, 11 (77) [Details]
(2014) 'AN IMAGING STRATEGY TO CHARACTERISE TAU PATHOLOGY IN VIVO IN A MODEL OF ALZHEIMER'S DISEASE USING MULTI-PARAMETRIC MRI'
Holmes, Holly E,Ismail, Ozama,Wells, Jack,O'Callaghan, James,Powell, Nicholas,Murray, Tracey,Ahmed, Zehshan,O'Neill, Michael,Collins, Emily,Johnson, Ross (2014) 'AN IMAGING STRATEGY TO CHARACTERISE TAU PATHOLOGY IN VIVO IN A MODEL OF ALZHEIMER'S DISEASE USING MULTI-PARAMETRIC MRI'. Alzheimer's & Dementia, 10 (44) [Details]
(2010) 'Quantitative MRI analysis of brain volume changes due to controlled cortical impact'
Colgan, Niall C,Cronin, Michelle M,Gobbo, Oliviero L,O'Mara, Shane M,O'Connor, William T,Gilchrist, Michael D (2010) 'Quantitative MRI analysis of brain volume changes due to controlled cortical impact'. Journal Of Neurotrauma, 27 (77):1265-1274 [Details]
(2010) 'Applying DTI white matter orientations to finite element head models to examine diffuse TBI under high rotational accelerations'
Colgan, Niall C.,Gilchrist, Michael D.,Curran, Kathleen M. (2010) 'Applying DTI white matter orientations to finite element head models to examine diffuse TBI under high rotational accelerations'. Progress in Biophysics and Molecular BiologyProgress in Biophysics and Molecular Biology, 103 (2–32–3):304-309 [Details]
(2005) 'Controlled impact device for simulating TBI with an animal model'
Gilchrist, MD,Colgan, N,O'Connor, WT,Smyth, A,Kenny, C (2005) 'Controlled impact device for simulating TBI with an animal model'. Acta Neurobiologiae ExperimentalisActa Neurobiologiae Experimentalis, 5 (6565) [Details]

Conference Publications

  Year Publication
(2017) Institute of physics and engineering and medicine conference in MR safety
J. Blackwell, W. Van der Putten, B. Tuohy and N. Colgan (2017) Experimental assessment of MRI-induced temperature change and SAR distributions in phantoms Institute of physics and engineering and medicine conference in MR safety [Details]
(2017) Joint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics
Niall Colgan, Wil Van der Putten and Brendan Tuohy (2017) Experimental and numerical assessment of MRI-induced temperature change and SAR distributions in phantoms . In: Eskola, H., Väisänen, O., Viik, J., Hyttinen, J eds. Joint Conference of the European Medical and Biological Engineering Conference (EMBEC) and the Nordic-Baltic Conference on Biomedical Engineering and Medical Physics [ARAN Link] [Details]